Hib (Haemophilus influenzae) Virus and the Vaccine

The Virus and It’s Effect

"Haemophilus influenzae (including Hib) is a bacterium that can cause a severe infection, occurring mostly in infants and children younger than five years of age. In spite of its name, Haemophilus influenzae does not cause influenza (the "flu"). There are six identifiable types of Haemophilus influenzae bacteria (a through f) and other non-identifiable types (called nontypeable). The one that most people are familiar with is Haemophilus influenzae type b, or Hib." - CDC, 2014

According to the CDC, "the most common types of invasive Haemophilus influenzae disease are:

  • Bacteremia (blood infection)
  • Meningitis (infection of the covering of the brain and spinal cord)
  • Epiglotittis (an inflammation of the windpipe; can cause breathing trouble)
  • Cellulitis (skin infection)
  • Infectious arthritis

U.S. Annual Mortality Rate for Hib

About 76 deaths per year

Estimated 768 died in U.S. annually between 1999 - 2008 - Clinical Infectious Diseases, 2011

During 1999-2008, the estimated mean annual incidence of H. influenzae infection was 1.62 cases per 100 000 population; 15.3% of cases were fatal. - Clinical Infectious Diseases, 2011

There are 5 types of Hib Vaccine

The five vaccines are: ActHIB; Hiberix; PedvaxHIB; Comvax; Pentacel and Menhibrix

Adverse Reactions from the Hib Vaccine

"VAERS received 29,747 reports after Hib vaccines; 5179 (17%) were serious, including 896 reports of deaths. Median age was 6 months (range 0-1022 months). Sudden infant death syndrome was the stated cause of death in 384 (51%) of 749 death reports with autopsy/death certificate records." - The Journal of Pediatrics, 2015

"Our analysis is further supported by a similar rise in diabetes after immunisation with H influenzae type b vaccine in the United States4 and United Kingdom. Furthermore, the increased risk of diabetes in the vaccinated group exceeds the expected decreased risk of complications of H influenzae meningitis...Thus diabetes induced by vaccine should not be considered a rare potential adverse event. The incidence of many other chronic immunological diseases, including asthma, allergies, and immune mediated cancers, has risen rapidly and may also be linked to immunisation." - British Medical Journal, 1999